Day and Night and its variants may refer to:

• Day and Night (1997 film) (Le jour et la nuit), a French drama directed by Bernard-Henri Lévy
• Day and Night (2004 Chinese film) (日日夜夜), directed by Wang Chao
• Day and Night (2004 Swedish film) (Dag och natt), directed by Simon Staho
• Day & Night (2010 film), an American animated short film produced by Pixar
• Day and Night (TV series), 2017, directed by Wang Wei

• Day and Night (album), 2012, by Gerd Dudek
• Day & Night (Kara EP), 2014, by South Korean girl group Kara
• Day & Night (Fifty Fifty EP) 2025, by South Korean girl group Fifty Fifty
• The Day and the Night, 1997 jazz saxophone album by Roscoe Mitchell
• Day & Night, a Chinese pop album by Janice Vidal, 2005
• Day and Night, a 1985 EP by Scottish rock group Balaam and the Angel

• "Day & Night" (Billie Piper song), 2000
• "Day & Night" (Isyss song), 2002
• "Day & Night", by Basshunter from Bass Generation, 2009
• "Day and Night", by The Drag Set, 1967
• "Day and Night", by The Wackers, 1973
• "Day and Night", by Loona from Hash, 2020
• "Day 'n' Nite", song by Kid Cudi, 2008
• Day and Night (Alamat song), 2023

• Day and Night: Poems 1924-1934, a book by New Zealand poet Ursula Bethell
• Day and Night, a pair of nude sculptures by Jacob Epstein
• Day and Night (cellular automaton)
• Day and Night (M. C. Escher), a 1938 woodcut
• Day and Night (painting), by Rufino Tamayo

• Day for night (disambiguation)
• Le jour et la nuit (disambiguation), the French equivalent
• Night and Day (disambiguation)
• Tag und Nacht (disambiguation), the German equivalent
• Daylight