Matsumoto (written: 松本 lit. "base of the pine tree") is the 15th most common Japanese surname.^[1] A less common variant is 松元.

• Akiko Matsumoto (松本 明子; born 1966), Japanese television personality and actress
• Ayaka Matsumoto (松本 亜弥華; born 1988), Japanese volleyball player
• Cazuo Matsumoto (born 1985), Brazilian table tennis player
• Chieko Matsumoto (松本ちえこ; 1959–2019), Japanese idol, singer and actress
• Chizuo Matsumoto (松本 智津夫; 1955–2018), better known as Shoko Asahara, Japanese cult leader and founder of Aum Shinrikyo
• Dai Matsumoto (松本 大; born 1959), Japanese voice actor
• Daiju Matsumoto (松本 大樹; born 1977), Japanese footballer
• Daiki Matsumoto (松本 大輝; born 1991), Japanese footballer
• Daisuke Matsumoto (politician) (松本 大輔; born 1971), Japanese politician
• David Matsumoto (born 1959), American psychologist, writer and judoka
• Eiichi Matsumoto (松本 栄一; 1915–2004), Japanese photographer
• Elisabetta Matsumoto, American physicist
• Fumiaki Matsumoto (松本 文明; born 1949), Japanese politician
• Gaku Matsumoto (松本 岳; born 1993), Japanese actor
• George Matsumoto (1922–2016), American architect and educator
• Go Matsumoto (松本 剛; born 1993), Japanese baseball player
• Gyoji Matsumoto (松本 暁司; 1934–2019), Japanese footballer
• H. Matsumoto, Japanese set decorator
• Hajime Matsumoto (松本 哉; born 1974), Japanese activist
• Matsumoto Hakuō I (初代 松本 白鸚; 1910–1982), Japanese kabuki actor
• Matsumoto Hakuō II (ニ代目 松本 白鸚; born 1942), Japanese kabuki actor
• Haruna Matsumoto (松本 遥奈; born 1993), Japanese snowboarder
• Hidehiko Matsumoto (松本 英彦; 1926–2000), Japanese jazz saxophonist and bandleader
• Hideto Matsumoto (松本 秀人; 1964–1998), better known as hide, Japanese musician
• Hideya Matsumoto (英也, 松本), Japanese mathematician
• Hiroka Matsumoto (松本 紘佳; born 1995), Japanese violinist
• Hiroko Matsumoto (松本 裕子; 1936–2003), Japanese model
• Hiroshi Matsumoto (engineer) (松本 紘; 1942–2025), Japanese engineer and atmospheric scientist
• Hiroya Matsumoto (松本 寛也; born 1986), Japanese actor
• Hiroya Matsumoto (footballer) (松本 大弥; born 2000), Japanese footballer
• Hiroyo Matsumoto (松本 浩代; born 1985), Japanese professional wrestler
• Hiroyuki Matsumoto (松本 浩幸; born 1989), Japanese footballer
• Hisato Matsumoto (松本 尚人; born 1984), Japanese swimmer
• Hitoshi Matsumoto (松本 人志; born 1963), Japanese comedian
• Matsumoto Ichiyō (松本 一洋; 1893–1952), Japanese painter
• Ikuo Matsumoto (松本 育夫; born 1941), Japanese footballer and manager
• Iyo Matsumoto (松本 伊代; born 1965), Japanese idol, singer, actress and television personality
• Izumi Matsumoto (まつもと 泉; 1958-2020), Japanese manga artist
• Jiichirō Matsumoto (松本 治一郎; 1887–1966), Japanese politician and businessman
• Jiro Matsumoto (松本 次郎; born 1970), Japanese manga artist
• Jōji Matsumoto (松本 烝治; 1877–1954), Japanese legal scholar and politician
• Jon Matsumoto (born 1986), Canadian ice hockey player
• Jun Matsumoto (松本 潤; born 1983), Japanese singer and actor
• Jun Matsumoto (politician) (松本 純; born 1950), Japanese politician
• Matsumoto Jun (physician) (松本 順; 1832–1907), Japanese physician
• Kaori Matsumoto (松本 薫; born 1987), Japanese judoka
• Kaoru Matsumoto (松本 香; born 1960), better known as Dump Matsumoto, Japanese professional wrestler
• Katsuaki Matsumoto (松本 勝明; 1928-2021), Japanese cyclist
• Katsuhiro Matsumoto (松元 克央; born 1997), Japanese swimmer
• Katsuji Matsumoto (松本 かつぢ; 1904–1986), Japanese illustrator and manga artist
• Matsumoto Kazu (松本 和; 1860–1940), Imperial Japanese Navy admiral
• Kazuhiko Matsumoto (松本 和彦), Japanese adult video director
• Keiji Matsumoto (松本 恵二; 1949–2015), Japanese racing driver
• Keijiro Matsumoto (松本 啓二朗; born 1986), Japanese baseball player
• Keisuke Matsumoto (松本 圭介; born 1988), Japanese footballer
• Kenjiro Matsumoto (松本 健次郎; born 1943), Japanese swimmer
• Kiyo A. Matsumoto (born 1955), American judge
• Kodai Matsumoto (松本 幸大; born 1980), Japanese baseball player
• Kohei Matsumoto (松本 孝平; born 1989), Japanese footballer
• Kohei Matsumoto (松本 孝平; born 1994), Japanese footballer
• Kohji Matsumoto (松本 耕二), Japanese mathematician
• Kōjirō Matsumoto (松本 孝次郎; 1870–1932), Japanese educationist
• Matsumoto Kōshirō VII (七代目 松本 幸四郎; 1870–1949), Japanese kabuki actor
• Matsumoto Kōshirō X (十代目 松本 幸四郎; born 1973), Japanese kabuki actor
• Lauren Matsumoto (born 1987), American politician and beauty pageant winner
• Leiji Matsumoto (松本 零士; 1938–2023), Japanese manga artist
• Lisa Matsumoto (1964–2007), American playwright
• Marika Matsumoto (松本 まりか; born 1984), Japanese actress
• Mark Matsumoto, American engineer
• Matsumoto Masanobu, Japanese swordsman
• Masaya Matsumoto (松本 昌也; born 1995), Japanese footballer
• Matatarō Matsumoto (松本 亦太郎; 1865–1943), Japanese psychologist
• Mayu Matsumoto (松本 麻佑; born 1995), Japanese badminton player
• Megumi Matsumoto (松元 恵; born 1977), Japanese voice actress
• Michiko Matsumoto (松本 路子; born 1950), Japanese photographer
• Miku Matsumoto (松本 未来; born 1981), Japanese mixed martial artist
• Mitsuo Matsumoto (born 1971), Japanese mixed martial artist
• Miwa Matsumoto (松本 美和; born 1971), Japanese voice actress
• Miyako Matsumoto (松本 都; born 1985), Japanese professional wrestler and actress
• Nagi Matsumoto (松本 凪生; born 2001), Japanese footballer
• Namika Matsumoto (松本 潮霞; born 1992), Japanese weightlifter
• Naoko Matsumoto, Japanese archaeologist
• Naomi Matsumoto (softball) (松本 直美; born 1968), Japanese softball player
• Naomichi Matsumoto (松本 直通; born 1961), Japanese physician and geneticist
• Nina Matsumoto (born 1984), Canadian cartoonist
• Norihiko Matsumoto (松本 徳彦; born 1936), Japanese photographer
• Nozomu Matsumoto (松本 望; 1905–1988), Japanese businessman and inventor
• Rei Matsumoto (松本 怜; born 1988), Japanese footballer
• Rie Matsumoto (松本 理恵; born 1985), Japanese anime director
• Rica Matsumoto (松本 梨香; born 1968), Japanese actress, voice actress and singer
• Rio Matsumoto (松本 莉緒; born 1982), Japanese actress, model and singer
• Roy Matsumoto (1914–2014), United States Army soldier
• Ryota Matsumoto (松本 怜大; born 1990), Japanese footballer

• Ryota Matsumoto (松本 良多), Japanese artist
• Ryu Matsumoto (松本 龍; 1951–2018), Japanese politician
• Ryūtarō Matsumoto (松本 隆太郎; born 1986), Japanese sport wrestler
• Ryuya Matsumoto (松本 竜也; born 1993), Japanese baseball player
• Sachi Matsumoto (松本 さち; born 1973), Japanese voice actress
• Sara Matsumoto (松本 沙羅; born 1992), Japanese voice actress
• Sayaka Matsumoto (born 1982), American judoka
• Seichō Matsumoto (松本 清張; 1909–1992), Japanese writer
• Shigeharu Matsumoto (松本 重治; 1899–1989), Japanese journalist
• Shingo Matsumoto (松本 慎吾; born 1978), Japanese sport wrestler
• Shinjiro Matsumoto (松本 真二郎), victim in Fukuoka family murder case, where Wei Wei was convicted and executed
• Sho Matsumoto (松本 翔; born 1992), Japanese footballer
• Shuna Matsumoto (松本 珠奈; born 1985), Japanese association football coach
• Shunichi Matsumoto (松本 俊一; 1897–1987), Japanese diplomat
• Shunsuke Matsumoto (松本 竣介; 1912–1948), Japanese painter
• Taishi Matsumoto (松本 泰志; born 1998), Japanese footballer
• Taiyō Matsumoto (松本 大洋; born 1967), Japanese manga artist
• Takahiro Matsumoto (松本 孝弘; born 1961), better known as Tak Matsumoto, Japanese musician
• Takashi Matsumoto (lyricist) (松本 隆; born 1949), Japanese lyricist and musician
• Takashi Matsumoto (poet) (松本 たかし; 1906–1956), Japanese poet
• Takatoshi Matsumoto (松本 昂聡; born 1983), Japanese footballer
• Takeaki Matsumoto (松本 剛明; born 1959), Japanese politician
• Takehisa Matsumoto (松本 武久; born 1980), Japanese Go player
• Takuya Matsumoto (松本 拓也; born 1989), Japanese footballer
• Tamaki Matsumoto (松元 環季; born 1999), Japanese voice actress and actress
• Temari Matsumoto (松本 テマリ), Japanese manga artist and illustrator
• Tetsuya Matsumoto (松本 哲也; born 1984), Japanese baseball player
• Tomo Matsumoto (マツモト トモ), Japanese manga artist
• Tortoise Matsumoto (born 1966), Japanese musician
• Tōru Matsumoto (松本徹) (born 1977), Japanese badminton player
• Toshio Matsumoto (松本 俊夫; 1932–2017), Japanese film director
• Toshio Matsumoto (dancer) (松本 利夫; born 1975), Japanese dancer and actor
• Ukyo Matsumoto (松本 享恭; born 1994), Japanese actor
• Wakana Matsumoto (松本 若菜; born 1984), Japanese actress
• Yasushi Matsumoto (松本 安司; born 1969), Japanese footballer
• Yasunori Matsumoto (松本 保典; born 1960), Japanese actor and voice actor
• Yayoi Matsumoto (松本 弥生; born 1990), Japanese swimmer
• Yohei Matsumoto (松本 洋平; born 1973), Japanese politician
• Yoshihiko Matsumoto (松本 慶彦; born 1981), Japanese volleyball player
• Yoshiyuki Matsumoto (松本 佳介; born 1971), Japanese shogi player
• Yuichi Matsumoto (松元 ユウイチ; born 1980), Brazilian baseball player
• Yuji Matsumoto (松本 裕治), Japanese information scientist
• Yuki Matsumoto (松本 祐樹; born 1989), Japanese footballer
• Yukihiro Matsumoto (まつもと ゆきひろ; born 1965), Japanese computer scientist, software programmer, writer and creator of the Ruby programming language
• Yukino Matsumoto (松本 雪乃; born 1970), Japanese table tennis player

• Asami Matsumoto (松本 朝海), a character in the manga series Nana
• Kiyonaga Matsumoto (松本 清長), a character in the manga series Case Closed
• Rangiku Matsumoto (松本 乱菊), a character in the manga series Bleach