ASIS may refer to:

• Anterior superior iliac spine, a bony projection of iliac bone

• A Study in Scarlet, an 1887 mystery novel by Sir Arthur Conan Doyle featuring Sherlock Holmes

• Ada Semantic Interface Specification (ISO/IEC 15291)
• Africa Social Impact Summit
• Alam Shah Science School, a fully residential school in Malaysia
• The American Society for Industrial Security, a professional organization focused on the security industry, now known as ASIS International.
• American Society for Information Science and Technology (ASIS&T), sometimes known as the American Society for Information Science (ASIS)
• Australian Secret Intelligence Service
• Avans School of International Studies, the business studies faculty of Avans University of Applied Sciences

• Automatic Surface Inspection Systems, see Machine vision

• As is (disambiguation)
• Ashish, an Indian male given name