Dennis the Menace may refer to either of two comic strip characters that both appeared in March 1951, one in the UK and one in the US.

• Dennis the Menace is the original title of a British comic strip, written and published in Dundee, which first appeared in The Beano on 12 March 1951 and became the longest-running strip in the magazine in 2004.
  • Various television adaptations of the comic strip:
    • Dennis the Menace and Gnasher (1996 TV series) is an animated television series based on the Beano comic strip, known internationally as Dennis And Gnasher.
    • Dennis the Menace and Gnasher (2009 TV series) was released on September 7, 2009.
    • Dennis & Gnasher: Unleashed! (2017 TV series) is the latest animated CGI series, first broadcast in November 2017.

• Dennis the Menace (U.S. comics), a daily US syndicated newspaper comic strip since March 12, 1951
  • Various television and film adaptations of the comic strip:
    • Dennis the Menace (1959 TV series), a CBS network live action television show
    • Dennis the Menace (1986 TV series), an animated TV series
    • The All-New Dennis the Menace, a 1993 animated television series
    • Dennis the Menace (1993 film), a live-action film released in 1993
      • Dennis the Menace (video game), based on the 1993 film
    • Dennis the Menace Strikes Again, a 1998 direct-to-video sequel of the 1993 film

• "Tennis the Menace", a 2001 episode of The Simpsons
• Dennis Kucinich, Mayor of Cleveland Ohio, From 1977 to 1979 who earned the nickname "Dennis the Menace" for bankrupting the City of Cleveland
• Dennis L. A. White, American actor and rapper who rapped under the name "Dennis da Menace"