DeLisi is an Italian surname. Notable people with that surname include:
- Charles DeLisi, Metcalf Professor of Science and Engineering at Boston University
- Lynn DeLisi, American psychiatrist
- Matt DeLisi, American sociologist
- Scott H. DeLisi, United States Ambassador to Uganda
- Mathieu "SuperTF" Delisi, retired professional Overwatch player and content creator
See also
- Ben de Lisi, American fashion designer