The Conquest of America is a name given to the European colonization of the Americas.
The term may also refer to:
- Conquest of America (miniseries), a 2005 TV miniseries
- The Conquest of America: The Question of the Other, a 1982 book by Tzvetan Todorov
- Conquest of America, a play-by-mail game by Agents of Gaming later renamed to Continental Conquest.