A group of people who control the anti-cancer weapon 'Seraph'.They are stationed at the 'Academy Base', a key point in the defence of humanity, and in case of emergency, they stand on the death line and hunt 'Cancers'^[1].

Motto: Beat Down, Rise Up

An elite squad appointed to the slash-and-burn unit after achieving excellent results in post-enlistment aptitude tests^[1].

Ruka Kayamori (茅（かや）森（もり）月（る）歌（か）, Kayamori Ruka)

Voiced by: Tomori Kusunoki

Singing voice: XAI

Birthday: June 24

Birthplace: Kanagawa

Seraph Name: Brave Blue

Seraph Code: "My legend begins now." (あたしの伝説（でんせつ）はこれから始（はじ）まる, Atashi no densetsu wa kore kara hajimaru)^[2]

The main character^[3][4]. Captain of Squad 31-A. Former guitarist and vocalist of the legendary rock band "She is Legend", she is a genuine rocker who has earned the nickname 'genius' for her overwhelming talent in writing lyrics and music^[5]. She formed the new 'She is Legend' with the six members of Squad 31-A. Basically, she is easy-going and doesn't think too deeply about anything, but she sometimes shows her bravery because of her love for her friends, especially when someone's life is about to disappear, and she never misses it. To others, she basically calls them by their full names, with the intention bonding with them. She is particularly close with Yuki in the same unit and often engages in gag exchanges with her.

Yuki Izumi (和泉（いずみ）ユキ, Izumi Yuki)

Voiced by: Ryoko Maekawa

Birthday: September 17

Birthplace: Niigata

Seraph Name: Rapid Fire

Seraph Code: "Hello, World"

Nickname from Ruka: Yukkī (ユッキー, Yukkī)

A member of the hacker group Orchid, a genius hacker with a track record of preventing World War III. A fan of 'She is Legend', to which Ruka belonged. Since joining the Seraph Unit, she has been pushed around by Ruka's shenanigans but also supports her kindly. Despite her intellectual appearance, her tone of voice is somewhat rough. In the new "She is Legend", she is the drummer and bandmaster.

Megumi Aikawa (逢（あい）川（かわ）めぐみ, Aikawa Megumi)

Voiced by: Anju Inami

Birthday: October 28

Birthplace: Osaka

Seraph Name: Clavis

Seraph Code: "Yer Savior has arrived" (救世主（きゅうせいしゅ）様（さま）のお出（で）ましや, Kyūseishu-sama no odemashiya)

Nickname from Ruka: Megumin (めぐみん, Megumin)

A feisty psychic from the Kansai region. While the limits of her psychic abilities are unknown, they haven't been of much use since joining the Seraph squadron. Even so, she believes she's the Chosen One destined to save the world. She has a one-sided rivalry with Ruka, whose reputation as a young musical genius gets on her nerves.

A timid psychic from Kansai. She believes that she is "the saviour who will save the world", even though she rarely using it since joining the Seraph squadron while it's unknown the limits of her psychic abilities. She has a one-sided rivalry with Ruka, who is hailed as a "genius". She plays guitar in the new 'She is Legend'.

Tsukasa Tojo (東城（とうじょう）つかさ, Tōjō Tsukasa)

Voiced by: Yurina Amami

Birthday: February 14

Birthplace: Tokyo

Seraph Name: Supreme Edge

Seraph Code: "There exists more than one truth." (真実（しんじつ）は一（ひと）つと限（かぎ）らない, Shinjitsu wa hitotsu to kagiranai)

Nickname from Ruka: Tsukasacchi (つかさっち, Tsukasacchi)

A self-proclaimed 'elite intelligence officer' with a perfect appearance. She knows a lot of useless information and takes pleasure in teaching Karen, also from Squad 31-A, the secrets of beautiful skin. In the new 'She is Legend', she plays the keyboard.

Karen Asakura (朝倉（あさくら）可憐（かれん）, Asakura Karen)

Voiced by: Yū Serizawa

Singing voice: Konomi Suzuki/Ayumu

Birthday: July 11

Birthplace: Tochigi

Seraph Name: Glitter Shadow

Seraph Code: "Reaping your last breath." (呼吸（こきゅう）をするように息の根（いきのね）を止（と）める, Kokyū o suru yō ni ikinone o tomeru)

Nickname from Ruka: Karerin (かれりん, Karerin) and Karen-chan (カレンちゃん, Karen-chan)

A gamer girl who is good at FPS. She prefers junk food that can be eaten with one hand so she can keep playing games. She has a cute personality, but she is a murderer with a split personality. She is in charge of twin vocals in the new 'She is Legend'.

Tama Kunimi (國（くに）見（み）タマ, Kunimi Tama)

Voiced by: Aoi Koga

Birthday: November 1

Birthplace: Kawasaki

Seraph Name: Phantom Weaver

Seraph Code: "Unsinkable." (天下一品（てんかいっぴん）, Tenkaippin)

Nickname from Ruka: Otama-san (おタマさん, Otama-san)

Former captain of a battleship that was lost in the Sea of ​​Okhotsk. She has a dim-witted personality but is unaware of it. She is self-conscious about her short height of 137cm. She adores Megumi, who is also in 31A and always protects her. She plays the bass in the new "She is Legend".

Motto: Love & Peace

A unit with a peaky composition.

Erika Aoi (蒼（あお）井（い）えりか, Aoi Erika)

Voiced by: Saki Miyashita

Birthday: July 7

Birthplace: Saitama

Seraph Name: Shooting Star

Seraph Code: "Peaceful memories upon thee." (どうか安寧（あんねい）な記憶（きおく）を, Dō ka anneina kioku o)

Nickname from Ruka: Aoi (蒼（あお）井（い）)

The captain of Squad 31B. She is a genius with the intellectual ability of "hyperthymesia" and always scores 100 in tests. However, she lacks self-confidence in herself and is always timid. Byakko, a member of the same unit, is her only source of comfort.

Ichigo Minase (水（みな）瀬（せ）いちご, Minase Ichigo)

Voiced by: Aimi

Birthday: January 15

Birthplace: Aichi

Seraph Name: Guilty Cracker

Seraph Code: "Burn in Inferno." (インフェルノに焼（や）かれな, Inferuno ni yaka re na)

Nickname from Ruka: Ichigo (いちご)

She and her sister, Sumomo, are assassins. Her favorite sport is baseball, and her favorite food is vegetable sticks. She is a rough and volatile person and is quick to point a gun at people, but she is a kind-hearted person who cares for her younger sister and sometimes shows a girlish side that is appropriate for her age.

Sumomo Minase (水（みな）瀬（せ）すもも, Minase Sumomo)

Voiced by: Yuyu Shoji

Birthday: September 6

Birthplace: Aichi

Seraph Name: Rainny Lull

Seraph Code: "Freeze in Nibelheim, meow." (ニブルヘイムで凍（こご）えろにゃ, Niburuheimu de kogoero nya)

Nickname from Ruka: Sumomo (すもも)

The younger sister of Ichigo Minase and an assassin. She always ends her sentences with "meow". She has a natural talent as an assassin and like her sister, is quick to point a gun at someone. Although she seems rather disinterested, she's dangerous when angered. Her favorite snack is 5 yen chocolate coins.

Seika Higuchi (樋口（ひぐち）聖（せい）華（か）, Higuchi Seika)

Voiced by: Aya Yamane

Birthday: November 8

Birthplace: Shiga

Seraph Name: Fatal Null

Seraph Code: "Show me an exciting death." (新鮮（しんせん）な死（し）を見（み）せてくれ, Shinsenna shi o misete kure)

Nickname from Ruka: Higumin (ひぐみん)

A researcher who works at the base's lab. She is a genius scientist knowledgeable about Seraphim. Her enthusiasm is insane, and she is interested in the "death of life, but she is completely indifferent to things that don't interest her. She has a very good appearance, but she has a severe hunched back, and she is so unfamiliar with beauty that even styling her hair is a hassle.

Kozue Hiiragi (柊木（ひいらぎ）梢（こずえ）, Hiiragi Kozue)

Voiced by: Ari Ozawa

Birthday: March 18

Birthplace: Aomori

Seraph Name: MANA

Seraph Code: (眠（ねむ）れ、イノセントレクイエム)

Nickname from Ruka: Koju (こじゅ)

A girl who can see ghosts^[6]. When she uncovers her left eye, concealed by an eye patch, she can help ghosts find peace^[6]. She is timid and often nervous yet speaks with firm resolve when necessary.

Byakko (ビャッコ, Byakko)

Voiced by:

Birthday: April 8

Birthplace: Iwate

Seraph Name: Vtra

Seraph Code: "Groar!" (ヴァゥーーーーーーー！)

Nickname from Ruka: Byakko (ビャッコ)

The only white tiger compatible with Seraph following military experiments. She possessed such high intelligence that it understands human speech and emotions. Initially shy around people, she only bonded with Aoi at first, but later grew attached to Sumomo once she began caring for it. Her favourite food is meat sticks and she is skilled at Othello. Bears a scar over its left eye, but is not one-eyed.

Bon Ivar Yamawaki (山脇（やまわき）・ボン・イヴァール, Yamawaki Bon Ivāru)

Voiced by: Sayaka Senbongi

Birthday: August 25

Birthplace: Kumamoto

Seraph Name: Love Reaper

Seraph Code: この世界は私の実験台よ

Nickname from Ruka: Wakki (ワッキー)

The leader of Squad 31C^[7]. A self-proclaimed mad scientist who seeks world domination, alongside her lackey, Yayoi Bungo. While she comes off as hot-headed and haughty, but in truth she is a kind and gentle girl who loves her friends and takes good care of them. She always wears an eye patch over her left eye. She researches and develops various items in her work, but none of them have any real use.

Seira Sakuraba (桜庭（さくらば）星羅（せいら）, Sakuraba Seira)

Miko Tenne (天（てん）音（ね）巫（み）呼（こ）, Tenne Miko)

Yayoi Bungo (豊後（ぶんご）弥生（やよい）, Bungo Yayoi)

Adelheid Kanzaki (神崎（かんざき） ・アーデルハイド, Kanzaki Āderuhaido)

Mari Satsuki (佐月（さつき）マリ, Satsuki Mari)

Yuina Shirakawa (白河（しらかわ）ユイナ, Shirakawa Yuina)

Monaka Tsukishiro (月（つき）城（しろ）最（も）中（なか）, Tsukishiro Monaka)

Miya Kiryu (桐生（きりゅう）美也（みや）, Kiryū Miya)

Chie Sugawara (菅原（すがわら）千恵（ちえ）, Sugawara Chie)

Hisame Ogasahara (小笠原（おがさはら）緋雨（ひさめ）, Ogasahara Hisame)

Satomi Kura (蔵（くら）里見（さとみ）, Kura Satomi)

Misato Nikaido (二階堂（にかいどう）三郷（みさと）, Nikaidō Misato)

Iroha Ishii (石井（いしい）色葉（いろは）, Ishii Iroha)

Fubuki Mikoto (命（みこと）吹雪（ふぶき）, Mikoto Fubuki)

Risa Murofushi (室伏（むろふし）理沙（りさ）, Murofushi Risa)

Akari Date (伊達（だて）朱里（あかり）, Date Akari)

Aina Mizuhara (瑞原（みずはら）あいな, Mizuhara Aina)

Ichiko Ohshima (大島（おおしま）一千子（いちこ）, Ōshima Ichiko)

Niina Ohshima (大島二以奈, Ōshima Niina)

Minori Ohshima (大島三野里, Ōshima Minori)

Yotsuha Ohshima

Isuzu Ohshima

Muua Ohshima

Mion Yanagi

Kanata Maruyama

Chiroru Matsuoka

Inori Natsume

Maki Kurosawa

Carole Reaper

Li Yingxia

Irene Redmayne

Vritika Balakrishnan

Maria de Angelis

Charlotta Skopovskaya