Up Close and Personal or variants may refer to:
- Up Close & Personal (film), a 1996 film starring Robert Redford and Michelle Pfeiffer
- Up Close & Personal with PZ, a 2011 Indian celebrity talk show hosted by actress Preity Zinta
Music
- Up Close and Personal Tour (disambiguation)
- Number Ones, Up Close and Personal, a concert tour by Janet Jackson
- Up Close and Personal Tour (Guns N' Roses), 2012
- Up Close and Personal Tour, McFly
- "Up Close and Personal", a 2006 single by South
Albums
- Up Close and Personal (Angie Martinez album), 2001
- Up Close and Personal (Judith Durham album), 2009
- Up! Close and Personal, Shania Twain DVD
- Up Close & Personal (Vicki Genfan album), 2006
- Up Close and Personal - Live at SWR1, by Ray Wilson
- Up Close and Personal, by Jay Perez
- Up Close And Personal! Live In Germany, by Demon
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