Spook is a synonym for ghost. Spook or spooks may also refer to:

• Spook (nickname), shared by several notable people
• Per Spook (born 1939), Norwegian fashion designer
• a racial slur referring to a black person

• Spook Bridge, an abandoned bridge over the Withlacoochee River, Georgia, United States
• Spook Cave, a flooded cave in Iowa, US
• Spook Hill, a gravity hill in Florida, US
• Spook (crater), a small crater in the Descartes Highlands of the Moon

• Spook (comics), a DC Comics enemy of Batman
• Spook, a character from the cartoon series Top Cat
• Spook, a character in the comic strip The Wizard of Id

• Spooks (1930 film), a 1930 Oswald the Lucky Rabbit short
• Spooks (1953 film), a 1953 Three Stooges short
• Spooks: The Greater Good, a British 2015 spy film

• Spook: Science Tackles the Afterlife, a 2005 non-fiction book by Mary Roach
• Spook's, a series of dark fantasy novels by Joseph Delaney
• Spook, a graphic novel by Joshua Starnes and Lisandro Estherren
• Spooks, a children's book by Colin and Jacqui Hawkins as part of their Picture Lions series
• Spooks, a comic book series by Larry Hama

• Spooks (TV series), a UK series broadcast from 2002 to 2011 (called MI-5 in some countries)
• Spooks: Code 9, a UK series broadcast in 2008

• Spooks (group), an American hip-hop band

• Spooks (album), a 2010 album by The Beautiful Girls
• Spooks: Original Comics Soundtrack, a 2008 album by Lalo Schifrin and Andy Garfield, based on the comics by Larry Hama

• "Spooks", by Dance Gavin Dance from the album Downtown Battle Mountain II
• "Spooks", by Jonny Greenwood (Radiohead) from the Inherent Vice soundtrack
• "Spooks!", by Louis Armstrong, released in 1954, later found on album Satchmo In Style
• "Spooks", by Marion Brown from the album Three for Shepp 1966
• "Spooks", by Pryda from the single Spooks / Do It
• "Spook", by Black Rebel Motorcycle Club from the album Wrong Creatures

• Spooks (video game), a 1985 video game

• "Spook", nickname for a Mine Protected Combat Vehicle, a Rhodesian armoured fighting vehicle
• "The Spook", emblem of the McDonnell Douglas F-4 Phantom II, a United States Navy fighter-bomber

• a concept in the philosophy of Max Stirner

• Spooked (disambiguation)
• Spooky (disambiguation)
• Secret agent (disambiguation)