The Seine is a river in France.

Seine may also refer to:

• Seine (department), a former administrative subdivision of France encompassing Paris and its immediate suburbs
• Seine River (disambiguation)
  • Seine River (Ontario), Canada
  • Seine River (Manitoba), Canada
  • Seine River (electoral district), Manitoba, Canada

• Seine, a type of fishing net, used in seine fishing
• MV Seine a Dutch coaster
• Seine (Van Gogh series), a group of paintings by Vincent van Gogh
• "La Seine", a 1948 song by Guy Lafarge
• "La Seine", a 2012 song by Vanessa Paradis

• "Jedem das Seine", a German proverb
• La Seyne, a commune in the Var department, France
• Zenne, a river in Belgium
• All pages with titles beginning with Seine