Milsom is a surname. Notable people by that name include:

• Robert Milsom (born 1987), English footballer.
• Nigel Milsom (born 1975), Australian painter.
• Veronica Milsom (born 1984), Australian radio presenter, comedian and actress.
• Jack Milsom (1907–1977), English footballer.
• Edward Milsom, rugby league footballer who played in the 1890s.
• S. F. C. Milsom (1923–2016), English legal historian.

• Milsom Rees