David Smith may refer to:

• David Paige Smith (1830–1880), American medical doctor and professor at Yale
• David Eugene Smith (1860–1944), American professor of mathematics
• D. M. Smith (1884–1962), American professor of mathematics at Georgia Tech
• David Smith (amateur mathematician), discoverer of an aperiodic tiling
• D. Nichol Smith (1875–1962), Scottish professor of literature at Oxford University
• David Chadwick Smith (1931–2000), Canadian professor of economics, Queen's University
• David Smith (chemical physicist) (1935–2023), British chemical physicist, University of Birmingham
• David C. Smith (historian) (1929–2009), American professor of history, University of Maine
• David Martyn Smith (1921–2009), American professor of forestry at Yale
• David Smith (botanist) (1930–2018), British professor of botany
• Dai Smith (historian) (born 1945), Welsh professor of history
• David J. Smith (physicist) (born 1948), Australian professor of physics at Arizona State
• David Livingstone Smith (born 1953), professor of philosophy at the University of New England
• David Smith (historian) (born 1963), British professor of history at Cambridge
• David K. Smith, British professor of chemistry at University of York
• David R. Smith (physicist), American physicist and professor of electrical and computer engineering at Duke University

• David Forbes Smith (1865–1923), Scottish architect
• David Smith (director) (1872–1930), English film director of the silent era
• David Stanley Smith (composer) (1877–1949), American classical composer, professor of music at Yale
• David Smith (sculptor) (1906–1965), American Abstract Expressionist
• David C. Smith (author) (born 1952), American novelist of heroic fantasy
• David Smith, Australian artist, founding member of the art collective Optronic Kinetics in 1970s Sydney
• David G. Smith, American singer-songwriter from the 1970s to the present
• David Bruce Smith (born 1958), American publisher, real estate executive
• David Alan Smith (actor) (born 1959), American actor and writer
• David Lee Smith (born 1963), American film actor
• David A. Smith (designer) (born 1968), British designer, glass embosser, sign writer
• David B. Smith (born 1977), American multi-disciplinary artist
• David Brian Smith (born 1981), English artist
• David Branson Smith (born 1984), American film screenwriter
• David P. Smith, American animator and voice actor, creator of Mixels (2014–2016)

• David Canfield Smith (born 1945), American computer scientist who invented graphical interface icons
• David A. Smith (computer scientist) (born 1957), American computer scientist and entrepreneur
• David L. Smith (hacker) (born c. 1968), author of the Melissa virus

• David Boyes Smith (1833–1889), deputy surgeon general of the Indian Medical Service
• David M. Smith (virologist) (born 1971), American translational research virologist
• David Weyhe Smith (1926–1981), American pediatrician and dysmorphologist

• David D. Smith (born 1950), American president and CEO of Sinclair Broadcast Group
• David Andrew Smith (born 1952), British journalist
• David Henry Smith (born 1954), economics editor of the UK Sunday Times
• David Smith (journalist) (born 1975), Washington, DC, Bureau Chief of the UK The Guardian

• David Smith (Victorian politician) (1861–1943), Australian politician
• David Smith (public servant) (1933–2022), Official Secretary to five Governors-General of Australia
• David Smith (Australian Capital Territory politician) (born 1970), Australian politician
• David Smith (Western Australian politician) (born 1943), Australian politician

• Sir David William Smith, 1st Baronet (1764–1837), Canadian soldier and politician
• David William Smith (born 1938), Ontario politician
• David Smith (Canadian senator) (1941–2020), Canadian lawyer and politician
• David Smith (Quebec politician) (born 1963), Canadian politician
• David Smith (justice), Canadian judge
• David Smith (Toronto politician), Ontario politician
• Dave Smith (Peterborough, Ontario politician), Ontario politician

• David L. Smith (politician) (1827–1902), American politician from Pennsylvania
• David Highbaugh Smith (1854–1928), American congressman
• David S. Smith (1918–2012), U.S. ambassador to Sweden
• D. Brooks Smith (born 1951), American federal judge
• Adam Smith (Washington politician) (David Adam Smith, born 1965), American congressman
• David Brock Smith, member of the Oregon House of Representatives
• David Smith (Florida politician) (born 1960), member of the Florida Legislature
• David Smith (Oklahoma politician), member of the Oklahoma House of Representatives
• David Burnell Smith (1941–2014), member of the Arizona House of Representatives
• David Tyson Smith, member of the Missouri House of Representatives

• David Smith (British Conservative politician) (1826–1886), British MP
• David Smith (British Labour politician), British MP for North Northumberland elected in 2024
• David Smith (judge) (1888–1982), New Zealand judge
• David Smith (Rhodesian politician) (1922–1996), politician in Rhodesia and Zimbabwe
• David Smith (spy), Berlin British Embassy security guard convicted for spying for Russia

• David Hyrum Smith (1844–1904), missionary of the Latter Day Saint movement
• David A. Smith (Mormon) (1879–1952), bishop and first president of the Mormon Tabernacle Choir
• David Smith (bishop) (1935–2024), English Bishop of Bradford

• David Smith (Gloucestershire cricketer) (1934–2003), English cricketer, 1956–1971
• David Smith (Derbyshire cricketer) (1940–2021), English cricketer
• David Smith (cricketer, born 1945), English cricketer
• David Smith (cricketer, born 1956), English cricketer
• David Smith (Tasmania cricketer) (born 1957), Australian cricketer for the Tasmanian Tigers
• David Smith (Sussex cricketer, born 1962), English cricketer
• David Smith (Warwickshire cricketer, born 1956), English cricketer
• David Smith (Warwickshire cricketer, born 1962), English cricketer
• David Smith (cricketer, born 1970), English cricketer
• David Smith (cricketer, born 1989), English cricketer

• David Smith (sportsman) (1884–1963), Australian rules footballer and cricketer, 1903–1914
• David Smith (footballer, born 1871), English professional footballer who played between 1890 and 1896
• David Smith (footballer, born 1875) (1875–1947), Scottish footballer
• David Smith (footballer, born 1968), English professional footballer who played between 1986 and 2003
• David Smith (footballer, born 1970), English professional footballer who played between 1989 and 2004
• David Smith (footballer, born 1993), Scottish professional footballer
• Dai Smith (rugby league) (David Smith), rugby league footballer who played in the 1900s for Salford
• David Smith (rugby league, born 1953), rugby league footballer who played in the 1970s and 1980s
• David Smith (rugby league, born 1967), Australian rugby league footballer who played in the 1980s and 1990s
• David Smith (rugby league, born 1968), English rugby league footballer who played in the 1980s and 1990s
• David Smith (rugby union, born 1986), Samoan rugby union footballer for Hurricanes, Blues, Auckland
• David Smith (rugby union, born 1988), English rugby union footballer
• David Smith (rugby union, born 1957), South African rugby union footballer

• Dave Smith (triple jumper) (born 1947), American triple jumper
• David Smith (hammer thrower, born 1962), English Olympic hammer thrower
• David Smith (hammer thrower, born 1974), English Olympic hammer thrower
• David Adley Smith II (born 1992), Puerto Rican high jumper
• David Smith (born 1991), British high jumper and competitor at the 2018 Commonwealth Games

• David Smith (sport shooter) (1880–1945), South African Olympic sport shooter
• David Smith (sailor) (1925–2014), American sailor and Olympic Champion
• Davey Boy Smith (1962–2002), British professional wrestler a.k.a. "The British Bulldog"
• David Miln Smith (born 1938), American adventure athlete and speaker
• David Smith (baseball historian) (born 1948), American baseball historian, statistician, professor of biology
• David Smith (racewalker) (born 1955), Australian Olympic race walker
• David Ross Smith, ice hockey defenceman
• Dave Smith (ice hockey) (born 1968), Canadian coach, former player, IHL
• David Smith (rower) (born 1978), British adaptive rower
• Davey Boy Smith Jr. (born 1985), Canadian professional wrestler, a.k.a. Harry Francis Smith
• David Smith (volleyball) (born 1985), American volleyball player
• David Smith (canoeist) (born 1987), Australian sprint canoeist
• David Smith (boccia) (born 1989), British Paralympic boccia player
• David Smith (curler), Scottish curler, first international competition was 1982
• David Smith (fighter), American mixed martial arts fighter
• David Smith (racing driver) (born 1950), Canadian stock car racing driver

• David John Smith (1907–1976), president of British retailer W. H. Smith, 1948–1968
• David M. Smith (Medal of Honor) (1926–1950), American soldier and Medal of Honor recipient
• David Smith (executive), Welsh banking and sporting administrator
• David Smith (murderer) (born 1956), English rapist and murderer
• David R. Smith (general) (born 1942), United States Air Force general
• David J. Smith (author), Canadian teacher and educational consultant, children's writer
• David Smith, co-founder of the Media Molecule video game development company
• David J. Smith, accountant and managing director of Post Office Limited before Paula Vennells

• Dave Smith (disambiguation)