The Big Cat may refer to:

• Johnny Lee Bench (born 1941), Oklahoma, baseball player
• Tom Erikson (born 1964), American amateur wrestler and mixed martial artist
• Andrés Galarraga (born 1961), Venezuelan baseball player
• Ernie Ladd (1938–2007), American wrestler and football player
• Leon Lett (born 1968), American football player
• Earl Lloyd (1928–2015), American basketball player
• Jamaal Magloire (born 1978), Canadian basketball player
• Miloslav Mečíř (born 1964), Slovak tennis player
• Johnny Mize (1913–1993), American baseball player
• Ronnie Robinson (basketball) (1951–2004), American basketball player
• Brad Sweet (born 1985), American professional race car driver
• James Williams (offensive lineman) (born 1968), American football player
• Cleveland Williams (1933–1999), American professional boxer
• Rayfield Wright (1945–2022), American football player
• Andrei Vasilevskiy (born 1994), Russian ice hockey player
• Evan "Big Cat" Williams (born 1948) Professional Golfer and World Long-Drive Champion

• The Big Cat (film), a 1949 film directed by Phil Karlson

• Big cat (disambiguation)
• The Cat (disambiguation)
• Big the Cat, a character in the Sonic the Hedgehog video games