RPC may refer to:

• Rational polynomial coefficient
• Reactive Plastic Curtain, a carbon-dioxide-absorbing device used in some rebreather breathing sets
• Regional Playback Control, a regional lockout technology for DVDs
• Remote procedure call, an inter-process communication technique in networked computing
  • Open Network Computing Remote Procedure Call, IETF RPC, aka "Sun RPC"
  • DCE/RPC, for Distributed Computing Environment by Open Software Foundation
  • JSON-RPC, a "JSON encoded" variant
  • XML-RPC, an "XML encoded" variant
• Resistive plate chamber, a simple type of particle detector used in experimental particle physics
• Reversed-phase chromatography, a chemistry technique
• Acorn Risc PC
• Rocket Pod Container, the interchangeable containers used to transport and launch missiles for use with the M270 Multiple Launch Rocket System
• Rotary phase converter, an electrical machine that converts power from one polyphase system (including frequency) to another, converting through rotary motion.

• RPC Group, UK packaging company
• Recorded Picture Company, a British film-production company
• Reformed Presbyterian Church (disambiguation), denominations following a Presbyterian form of Christianity
• Regent's Park College, a permanent private hall of Oxford University
• RPC Fort (Research and Production Company Fort), a Ukrainian weapons manufacturer
• Research Policy Council, the executive management team for the Congressional Research Service, a division of the Library of Congress
• Royal Parks Constabulary, a police force which patrolled the eight Royal Parks of London and a number of other locations in London, 1974–2004
• RPC, Inc., a North American oil services business
• RPC, a Brazilian television network affiliated with TV Globo in the state of Paraná

• Reports of Patent, Design and Trademark Cases, a case-law journal published by the Oxford University Press on behalf of the UK Intellectual Property Office
• Revolutionary Policy Committee, a faction within UK Independent Labour Party during the 1930s
• Reynolds Porter Chamberlain, a law firm based in London
• Revised Penal Code of the Philippines
• Rules of Professional Conduct, relating to U.S. lawyers' ethical rules, see American Bar Association Model Rules of Professional Conduct

• Russian Paralympic Committee
  • RPC, the IPC code used for Russian Olympic Committee athletes:
    • Russian Paralympic Committee athletes at the 2020 Summer Paralympics
    • Russian Paralympic Committee athletes at the 2022 Winter Paralympics

• Recurrent pyogenic cholangitis, a medical condition
• Red Paraguaya de Comunicación, a TV operator in Paraguay
• Rei Publicae Constituendae, part of the title of the members of the second triumvirate, appearing on Roman coins
• République populaire de Chine, República popular China, República popular da China, the French, Spanish and Portuguese names for the People's Republic of China
• RPC, a Panamanian national television network

• All pages with titles beginning with RPC
• All pages with titles containing RPC