Peppe is a given name, nickname (often a short form of Giuseppe) and surname which may refer to:

• Giuseppe Cataldo (1938−2011), Italian mobster
• Giuseppe Durato (born 1992), Italian manga artist
• Peppe Eng (born 1948), Swedish sports journalist and television presenter
• Peppe Lanzetta (born 1956), Italian actor
• Peppe Femling (born 1992), Swedish biathlete
• Giuseppe Piromalli (born 1921) (1921–2005), Italian crime boss
• Giuseppe Poeta (born 1985), Italian basketball player
• Audrey Peppe (1917–1992), American figure skater
• Carlos Peppe (born 1983), Uruguayan footballer
• Rodney Peppé (born 1934), British author and illustrator

• Peppe, in the 1860 opera Rita

• Peppes Pizza, a Norwegian pizza chain
• Pepe (disambiguation)