Lorenzo may refer to:

• Lorenzo (name)

• San Lorenzo Island (Peru), sometimes referred to as the island of Lorenzo

• Lorenzo, Illinois
• Lorenzo, Texas
• San Lorenzo, California, formerly Lorenzo
• Lorenzo State Historic Site, house in New York State listed on the National Register of Historic Places

Films and television

• Lorenzo (film), an animated short film
• Lorenzo's Oil, a film based on a true story about a boy suffering from Adrenoleukodystrophy and his parents' journey to find a treatment.
• Lorenzo's Time, a 2012 Philippine TV series that aired on ABS-CBN

Music

• Lorenzo (rapper), French rapper
• "Lorenzo", a 1996 song by Phil Collins

• List of storms named Lorenzo
• Lorenzo (electronic health record), used at some NHS trusts in the United Kingdom

• San Lorenzo (disambiguation)
• De Lorenzo
• di Lorenzo
• Lorenzen (disambiguation)