Nuria Párrizas Díaz was the defending champion^[1] but chose to participate at the 2022 French Open instead.

Elisabetta Cocciaretto won the title, defeating Ylena In-Albon in the final, 6–2, 6–2.

	Semifinals							Final
	1	Ylena In-Albon	6	7
	5/WC	Sara Errani	4	5
								1	Ylena In-Albon	2	2
								4	Elisabetta Cocciaretto	6	6
	4	Elisabetta Cocciaretto	7	6
	Q	Dalila Jakupović	5	2

	First round							Second round							Quarterfinals							Semifinals
	1	Y In-Albon	6	6
		K Gerlach	1	2				1	Y In-Albon	5	6	7
		M Di Giuseppe	3	0r				Q	T Würth	7	3	5
	Q	T Würth	6	1											1	Y In-Albon	6	6
		D Seguel	6	5	2											M Zacarías	1	1
		M Zacarías	4	7	6				M Zacarías	6	0	6
		D Vismane	6	0					D Vismane	4	6	3
	7	S Vögele	3	0r																		1	Y In-Albon	6	7
	3	L Stefanini	6	4	4																	5/WC	S Errani	4	5
	Q	OG Simion	2	6	6			Q	OG Simion	3	2
		C Ferrando	2	6	4				B Haas	6	6
		B Haas	6	4	6											B Haas	5	6	2
		B Gatica	6	4	6										5/WC	S Errani	7	1	6
	Q	S Sakellaridi	4	6	1				B Gatica	6	1	1
		F Di Sarra	0	63				5/WC	S Errani	4	6	6
	5/WC	S Errani	6	77

	First round							Second round							Quarterfinals							Semifinals
	8	S Waltert	4	7	6
	WC	A Raggi	6	5	0			8	S Waltert	6	6
		N Vikhlyantseva	4	6	6				N Vikhlyantseva	4	1
		T Babos	6	1	2										8	S Waltert	5	3
		E Arango	6	3											4	E Cocciaretto	7	6
	Q	L Sun	4	0r					E Arango	6	3	3
	Q	A Turati	3	5				4	E Cocciaretto	3	6	6
	4	E Cocciaretto	6	7																		4	E Cocciaretto	7	6
	6	A Tikhonova	0	6	6																	Q	D Jakupović	5	2
	WC	N Brancaccio	6	4	3			6	A Tikhonova	6	3	6
	Q	L Pigato	6	6				Q	L Pigato	3	6	4
	Q	E Chong	1	2											6	A Tikhonova	6	5	2
	Q	D Jakupović	6	6											Q	D Jakupović	1	7	6
		E-s Liang	3	0				Q	D Jakupović	4	6	6
	WC	D Chiesa	77	6				WC	D Chiesa	6	4	0
	2	K Baindl	65	2

• Main Draw