Francis Sweeney may refer to:
- Francis E. Sweeney (1934–2011), American judge and politician
- Francis J. Sweeney (1862–1921), Canadian lawyer and politician
- Dr. Francis E. Sweeney (1894–1964), suspected to be the Cleveland Torso Murderer
See also
- Frances Sweeney (1908–1944), American journalist and activist
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