This tournament took place between April 9 and 15, 2001.

Carlos Moyá was the defending champion but did not compete that year.

Juan Carlos Ferrero won in the final 7–6^(7–3), 4–6, 6–3 against Félix Mantilla.

	Semifinals							Final
	1	Juan Carlos Ferrero	6	6
		Albert Portas	3	1
								1	Juan Carlos Ferrero	77	4	6
								Q	Félix Mantilla	63	6	3
	5	Andrei Pavel	2	6	2
	Q	Félix Mantilla	6	3	6

	First round							Second round							Quarterfinals							Semifinals
	1	J C Ferrero	6	77
		H Levy	3	62				1	J C Ferrero	6	6
		C Doseděl	6	6					C Doseděl	3	0
	WC	E Couto	3	4											1	J C Ferrero	6	6
		K Kučera	6	77											Q	A Montañés	2	4
		N Davydenko	3	63					K Kučera	3	3
	Q	A Montañés	6	6				Q	A Montañés	6	6
	6	M Chang	1	3																		1	J C Ferrero	6	6
	3	D Hrbatý	6	7																			A Portas	3	1
		M Youzhny	1	5				3	D Hrbatý	6	6
	WC	T Sousa	5	4					J Siemerink	1	3
		J Siemerink	7	6											3	D Hrbatý	2	4
		G Pozzi	3	6	3											A Portas	6	6
		A Portas	6	4	6				A Portas	62	6	6
		G Coria	711	6					G Coria	77	4	1
	7	N Lapentti	69	0

	First round							Second round							Quarterfinals							Semifinals
	5	A Pavel	6	6
	Q	X Malisse	1	1				5	A Pavel	6	6
	Q	J A Viloca	2	64					D Sánchez	4	1
		D Sánchez	6	77											5	A Pavel	78	78
		M Tabara	3	4											WC/4	F Squillari	66	66
		A Martín	6	6					A Martín	3	6	3
		C Rochus	4	63				WC/4	F Squillari	6	2	6
	WC/4	F Squillari	6	77																		5	A Pavel	2	6	2
	8	A Costa	4	2																		Q	F Mantilla	6	3	6
		M Hipfl	6	6					M Hipfl	5	6	6
		J Balcells	6	3					J Balcells	7	4	0
		A Medvedev	2	0r												M Hipfl	6	3	1
		J Novák	6	4	3										Q	F Mantilla	3	6	6
	Q	F Mantilla	4	6	6			Q	F Mantilla	7	6
		S Koubek	4	1				2	T Henman	5	1
	2	T Henman	6	6

• 2001 Estoril Open draw
• 2001 Estoril Open Qualifying draw