William or Bill Webb may refer to:

• William Benning Webb (1825–1896), American politician and attorney
• William C. Webb (1824–1898), member of the Wisconsin State Assembly and the Kansas House of Representatives
• William George Webb (1843–1905), British Member of Parliament for Kingswinford, 1900–1905
• William Hoste Webb (1820–1890), Quebec lawyer and political figure
• William R. Webb (1842–1926), U.S. Senator from Tennessee
• William Wilson Webb (1826–1894), Ontario businessman and political figure
• William Webb (Victorian politician), MP in the Victorian Legislative Assembly from 1889 to 1904

• B. W. Webb (William Wilson Webb Jr., born 1990), American football cornerback
• William Webb (boxer) (1882–?), British Olympic bronze medal (1908) bantamweight boxer
• William Webb (rower) (1880–1960), New Zealand World Champion rower
• Bill Webb (pitcher) (1913–1994), Major League Baseball player
• Bill Webb (rugby union) (1868–c. 1931), Australian rugby union player
• Bill Webb (Australian footballer) (1883–1947), Australian rules footballer
• Bill Webb (second baseman) (1895–1943), Major League Baseball player
• William Earl Webb (1897–1965), Major League Baseball outfielder
• William Webb (cricketer, born 1872) (1872–1913), New Zealand cricketer
• William Webb (cricketer, born 1898) (1898–1969), English cricketer
• William Webb (diver), British Olympic diver

• Boogie Bill Webb (1924–1990), American blues guitarist and singer
• Chick Webb (William Henry Webb, 1905–1939), American jazz and swing musician
• William Webb (composer) (c. 1600–1657), English musician and song composer

• Sir William Webb (judge) (1887–1972), Australian judge
• William A. Webb (1824–1881), American Civil War sailor
• Suhaib Webb (William Webb, born 1972), American Islamic activist
• William Alfred Webb (1878–1936), American and Australian railway administrator
• William Frederick Webb (1829–1899), wealthy British land owner
• William H. Webb (1816–1899), American shipbuilder, naval architect, industrialist and philanthropist
• William James Webb (1830–1904), English painter
• William J. Webb, Canadian egalitarian theologian known for his 'redemptive-movement' hermeneutic
• William Seward Webb (1851–1926), American doctor, financier, railroad president, and well-connected businessperson
• William Snyder Webb (1882–1964), American anthropologist
• William Trego Webb (1847–1934), educationist and author
• William Walter Webb (1857–1933), American Episcopal bishop
• Bill Webb (game designer), role-playing game designer
• William Webb (naturalist) (1834?–1897), Australian collector and trader of plants and animals
• William Webb (priest) (1825–1896), Archdeacon of Grenada
• William Webb (Master of Clare College, Cambridge) (1775–1856), English academic
• William Wilfrid Webb (1857–1911), English officer and physician in the Bengal Army and the Indian Medical Service

• Billy Webb's Amazing Stories, CBBC mini-series
• William Webb Ellis (1806–1872), English Anglican clergyman; the man who is said to have invented rugby
• William Webb Follett (1796–1845), English lawyer
• William Webb Venable (1880–1948), U.S. Representative from Mississippi
• William Webbe (disambiguation)