IWC may refer to:

• Industrial Welfare Commission, Californian wage regulation body
• Institute for Workers' Control, a defunct British Marxist organisation
• International Water Centre, provides education and training, applied research and expert services in integrated water resource management
• International Whaling Commission, international body regulating whaling
• International Wheat Council, former name of the International Grains Council
• International Wolf Center, a wolf education facility based in Minnesota
• Irish Wildbird Conservancy, former name of BirdWatch Ireland

• IAAF World Challenge, an annual global circuit of fourteen one-day athletics competitions organized by the IAAF
• International Wheelset Congress, an annual international rail conference
• UIAA Ice Climbing World Cup, and annual tour event that is also known as the IWC

• Industrial Water Cooling, a cooling tower manufacturer in Johannesburg, South Africa
• Imperial War Cabinet, a place in London, now a tourist attraction
• International Watch Company, a luxury Swiss watch manufacturer

• Inch of water (Inches Water Column), a measure of pressure
• Internet wrestling community, a nickname given to online postings or forums by fans of professional wrestling
• Iowa Wesleyan College, a liberal arts college located in Mount Pleasant, Iowa
• International Wrestling Cartel, a professional wrestling promotion based in Pittsburgh