TAM may refer to:

• Thioacetamide, an organosulfur compound
• Tumor-associated macrophage, a class of immune cells
• Transparent Anatomical Manikin, an educational model

• Tanque Argentino Mediano, the main battle tank of Argentina
• Technological Association Malaysia, a learned society
• Technology acceptance model, an information systems theory
• Teen Age Message, interstellar radio transmissions
• Telecom Application Map
• Telephone answering machine
• Twentieth Anniversary Macintosh, a limited-edition personal computer released by Apple in 1997

• TAM – Transporte Aéreo Militar, Bolivian airline
• TAM Air, a Georgian airline
• TAM Airlines, now known as LATAM Brasil
• Tovarna avtomobilov Maribor, a former Slovenian commercial vehicle manufacturer,
• Transports de l'Agglomération de Montpellier (TaM), a public transport company in France
• IATA airport code of General Francisco Javier Mina International Airport, Tampico, Mexico
• National Rail code of Tamworth railway station, England
• TAM Management, Georgia
• Tbilisi Aircraft Manufacturing, Georgia
• MTR station code of Tamar station, Hong Kong
• MRT station abbreviation of Tampines MRT station, Singapore

• Tam Lin, in a Scottish Borders ballad
• Tam Sventon, a private detective in Swedish children's novels
• River Tam, in the Firefly television series
• Simon Tam, in the Firefly television series
• Tấm, in the Vietnamese fairy tale The Story of Tam and Cam
• Tam Song, in the Keeper of the Lost Cities series

• Tam (name), a list of people with the first name, nickname or last name
• Tam cap
• Tam o' shanter (cap), bonnet from Scotland
• Rastacap, Rastafarian cap also known as a tam
• TAM (theatre), a theatre in North Rhine-Westphalia, Germany
• TAM Media Research, an Indian television audience measurement company
• TAM Mild Jalapeño, developed by Texas A&M University
• Toyota Astra Motor, an Indonesian automotive company
• Cyclone Tam (2006)
• The Amaz!ng Meeting, conference on critical thinking
• Total addressable market, for a product or service
• Mount Tamalpais, California, known locally as Mount Tam
• Tainan Art Museum, a museum in Tainan, Taiwan
• Tamalpais High School, California, United States, often abbreviated as Tam
• Picul or tam, a traditional Asian unit of weight
• ISO 639-3 language code of the Tamil language
• Team Action Management, programme that Albert S. Humphrey was involved with
• Tense–aspect–mood (or Tense–aspect–mood–evidentiality, abbreviated as tame), refers to a group of grammatical categories in the study of linguistics.
• tāṃ, the seed syllable of Green Tara

• TAM 5 or The Spirit of Butts' Farm, the first model plane to cross the Atlantic Ocean
• Tams (disambiguation)
• Tamtam (disambiguation)