Saint Blaise was a physician and bishop of Sebaste, martyred in 316.

Saint Blaise may also refer to:

• Saint Blaise of Amorion (died 908)
• Blaise of Caesarea Cappadociae a.k.a. Blaise the Herdsman, an early martyr (fl. 3rd c.)

In Canada:

• Saint-Blaise-sur-Richelieu, Quebec, a municipality in the province of Quebec

In France:

• Saint-Blaise, Alpes-Maritimes, in the department of Alpes-Maritimes
• Saint-Blaise, Haute-Savoie, in the department of Haute-Savoie
• Saint-Blaise-du-Buis, in the department of Isère
• Saint-Blaise-la-Roche (St. Blasien (bei Rappoltsweiler)), in the department of Bas-Rhin
• L'Hôpital-Saint-Blaise, a village and commune in the department of Pyrénées-Atlantiques
• Lentillac-Saint-Blaise, a village and commune in the department of Lot

In Germany:

• Kolleg St. Blasien a Catholic boarding school
• Otto of St. Blasien was a German Benedictine chronicler
• St Blaise, the English name for the town of Sankt Blasien, in Baden-Württemberg
• St. Blaise Abbey in the Black Forest
• St. Blaise church in Balve, in Westphalia

In Switzerland:

• Saint-Blaise, Neuchâtel, a municipality in the canton of Neuchâtel

In the United Kingdom:

• St. Blaise's Well, a well in Bromley
• St Blaise, an alternate spelling for St Blazey in Cornwall

• St. Blaise (horse) winner of the 1883 Epsom Derby

• San Blas (disambiguation)
• San Biagio (disambiguation)
• Blaise (disambiguation)
• Blasius (disambiguation)
• The Bishop Blaize, a pub in Stretford, Greater Manchester