Soyuz TM-34 was the fourth Soyuz mission to the International Space Station (ISS).^[1] Soyuz TM-34 was launched by a Soyuz-U launch vehicle.

Position	Launching crew	Landing crew
Commander	Yuri Gidzenko, RSA Third and last spaceflight	Sergei Zalyotin, RSA Second and last spaceflight
Flight Engineer	Roberto Vittori, ESA First spaceflight	Frank De Winne, ESA First spaceflight
Spaceflight Participant/Flight Engineer	Mark Shuttleworth, SA Only spaceflight Tourist	Yury Lonchakov, RSA Second spaceflight

• Docked to ISS: April 27, 2002, 07:55 UTC (to nadir port of Zarya)
• Undocked from ISS: November 9, 2002, 20:44 UTC (from nadir port of Zarya)

This was the 17th crewed mission to ISS.

Soyuz TM-34 was a Russian Soyuz TM passenger transportation craft that was launched by a Soyuz-U rocket from Baikonur at 06:26 UT on 25 April 2002. It carried two cosmonauts and a South African tourist, Mark Shuttleworth, to the International Space Station (ISS). Shuttleworth performed some biology experiments, as he carried a live rat and sheep stem cells. All three returned on Soyuz TM-33 after an eight-day mission.

Soyuz TM-34 was the final flight of the Soyuz-TM variant, due to its replacement by the upgraded Soyuz-TMA.^[1] It was also the last crewed vehicle to launch atop the Soyuz-U rocket, although the Soyuz-U continued to launch uncrewed vehicles until 2017.