Nisqually, Niskwalli, or Nisqualli may refer to:

• Nisqually people, a Coast Salish ethnic group
• Nisqually Indian Tribe of the Nisqually Reservation, federally recognized tribe
  • Nisqually Indian Reservation, the tribe's reservation in Thurston County
  • Nisqually language, a Southern Puget Sound Salish

• Billy Frank Jr. Nisqually National Wildlife Refuge, a protected area in the Nisqually River estuary
• Fort Nisqually, the first European trading post on Puget Sound
• Lake Nisqually was a proglacial lake in Washington state.
• Nisqually Mission, a Methodist station
• Nisqually River, located between Thurston and Pierce counties

• Nisqually Glacier on Mount Rainier
• Lake Nisqually was a prehistoric lake in the lower basin of Puget Sound and the Nisqually River.
• MV Nisqually, a Steel Electric-class ferry previously part of the Washington State Ferries system
• Nisqually, the former cargo ship SS Suremico which was converted into a scow and lost in the Battle of Wake Island
• Nisqually earthquake of 2001 in Washington
• Nisqually-1, a specimen of Populus trichocarpa, whose genome was sequenced
• Diocese of Nesqually