The Journal of Molecular Biology is a biweekly peer-reviewed scientific journal covering all aspects of molecular biology. It was established in 1959 by Academic Press in London.^[1][2] It is currently published by Elsevier. The editor-in-chief is Peter Wright (The Scripps Research Institute).

The journal is abstracted and indexed in:

According to the Journal Citation Reports, the journal has a 2023 impact factor of 4.7.^[9]

Some of the most highly cited articles that have appeared in the journal are:

• Monod, J.; Wyman, J.; Changeux, J.-P. (1965). "On the Nature of Allosteric Transitions: A Plausible Model". Journal of Molecular Biology. 12: 88–118. doi:10.1016/S0022-2836(65)80285-6. PMID 14343300., in which Jacques Monod, Jeffries Wyman, and Jean-Pierre Changeux presented the MWC model, that explained the cooperativity exhibited by allosteric proteins, such as hemoglobin.
• Southern, E. M. (1975). "Detection of specific sequences among DNA fragments separated by gel electrophoresis". Journal of Molecular Biology. 98 (3): 503–517. doi:10.1016/S0022-2836(75)80083-0. PMID 1195397., in which Edwin Southern presented the first description of nucleic acid blotting, a technique that revolutionized the field of molecular biology.
• Smith, T.; Waterman, M.S. (1981). "Identification of common molecular subsequences". Journal of Molecular Biology. 147 (1): 195–197. CiteSeerX 10.1.1.63.2897. doi:10.1016/0022-2836(81)90087-5. PMID 7265238., in which the Smith–Waterman algorithm for determining the degree of homology of DNA, RNA, or protein sequences was first described.
• Altschul, Stephen; Gish, Warren; Miller, Webb; Myers, Eugene; Lipman, David (1990). "Basic local alignment search tool". Journal of Molecular Biology. 215 (3): 403–410. doi:10.1016/S0022-2836(05)80360-2. PMID 2231712., in which the nucleic acid and protein homology search algorithm known as BLAST was originally described.

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