A Graphics processing unit, or GPU, is a special stream processor used in computer graphics hardware.
GPU may also refer to
- Gambia Press Union
- General Public Utilities, a defunct American electric utility
- General Purpose Uniform, of the Royal Australian Air Force
- Global Peace and Unity, an annual Muslim conference
- Ground power unit, used to power aircraft on the ground
- State Political Directorate (Russian: Государственное политическое управление, Gosudarstvennoye Politicheskoye Upravlenie), the secret police of the RSFSR and USSR from 1922 to 1923