Dehydroglycine is the organic compound with the formula HNCHCO2H. This rarely observed species is invoked as the product of oxidation (dehydrogenation) of glycine by glycine oxidase (ThiO), which is a step in the biosynthesis of thiamin.[1] It is also invoked as a product of the radical SAM-induced fragmentation of tyrosine.[2] It is an imino acid.
References
- ^ Begley, Tadhg P.; Ealick, Steven E. (2010). "Thiamin Biosynthesis". Comprehensive Natural Products II. pp. 547–559. doi:10.1016/B978-008045382-8.00148-9. ISBN 9780080453828.
- ^ Britt, R. David; Rao, Guodong; Tao, Lizhi (2020). "Bioassembly of complex iron–sulfur enzymes: Hydrogenases and nitrogenases". Nature Reviews Chemistry. 4 (10): 542–549. doi:10.1038/s41570-020-0208-x. PMC 8023223. PMID 33829110.
