3-dehydroquinate synthase II (EC 1.4.1.24, DHQ synthase II, MJ1249 (gene), aroB' (gene)) is an enzyme with systematic name 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating).[1] This enzyme catalyses the following chemical reaction
- 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ 3-dehydroquinate + NH3 + NADH + H+
The enzyme was isolated from the archaeon Methanocaldococcus jannaschii.
References
- ^ White RH (June 2004). "L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii". Biochemistry. 43 (23): 7618–27. doi:10.1021/bi0495127. PMID 15182204.
External links
- 3-dehydroquinate+synthase+II at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
