Eusébio (1942–2014) was a Portuguese footballer.

Eusebio or Eusébio may also refer to:

• Eusebio (name)

• Cayo Eusebio [es], Cuban island
• Eusébio, Ceará, Brazilian municipality
• Eusebio Ayala, Paraguay, Paraguayan city and district

• Avenida Eusebio Ayala [es], avenue in Asunción, Paraguay
• Calle Eusebio Estada [es], street in Palma de Mallorca, Spain
• Crypt of Sant'Eusebio, remanent of a church in Pavia, Italy
• Jose Eusebio Boronda Adobe, a Monterey colonial style California historical landmark
• Ponte Eusébio Matoso [pt], bridge in Saão Paulo, Brazil
• Sant'Eusebio, church in Rome
• Statue of Eusebio Kino, bronze sculpture depicting Eusebio Kino

• Autódromo Eusebio Marcilla, motorsports circuit in Junín, Argentina
• Eusébio Cup, Portuguese football match hosted by S.L. Benfica
• Eusébio de Queirós Law, Brazilian law enacted in 1850 to abolish slavery
• Eusébio Macário [pt], 1879 novel by Camilo Castelo Blanco
• KC Eusebio, action shooting competitor
• Premio Eusebio Lorenzo Baleirón, poetry prize of Dodro, Spain
• Trofeo Eusebio Vélez [es], Spanish amateur cycling event

• Eusebi (name)
• Eusebia (disambiguation)
• Eusebius (disambiguation)