49er, Forty-niner or Forty Niner most often refers to:

• A miner or other person who took part in the 1849 California Gold Rush
• San Francisco 49ers, an American football team

49er, Forty-niner or Forty Niner may also refer to:

• Charlotte 49ers, athletic teams of the University of North Carolina at Charlotte
• Long Beach State 49ers, nickname for the athletic teams of California State University, Long Beach
• Yuba 49ers, athletic teams of Yuba College
• 49er (dinghy), an Olympic class of racing dinghy
• Forty Niner (horse), an American Thoroughbred racehorse
• TKS 49ers, a German basketball team

• 49ers (band), an Italian Italo house and Eurodance project
  • 49ers (album), 1990
• The 49ers, an American hip-hop duo
• "49er", a song by American heavy metal band Riot from their 1979 album Narita

• The Forty-Niners (1932 film), an American Western directed by John P. McCarthy
• The Forty-Niners (1954 film), an American Western directed by Thomas Carr

• 49er Fire, a 1988 California wildfire in Nevada and Yuba counties
• 49er flapjack, a sourdough crepe
• Top 10: The Forty-Niners, a novel by Alan Moore and Gene Ha
• The Forty-Niners, or the Year 24 Group, a group of shōjo manga artists
• The 49ers, a group of Cathay Pacific Airways pilots fired in 2001
• 49er, the lowest initiated rank in Triad
• A 4.9% strength ale brewed by the Ringwood Brewery
• A member of the Canadian Expeditionary Force 49th Battalion
• The Forty-Niner (passenger train), 1937–1941

• 49 (number)
• Miner 2049er, a 1982 video game
• Forty-Eighters, Europeans involved in the revolutions of 1848
• Niner (disambiguation)
• 29er (disambiguation)