The following highways are numbered 378:
Canada
Japan
United States
Interstate 378 (former)
U.S. Route 378
Georgia State Route 378
Louisiana Highway 378
Maryland Route 378 (unsigned)
Nevada State Route 378 (former)
New Mexico State Road 378
New York State Route 378
Ohio State Route 378
Pennsylvania Route 378
Puerto Rico Highway 378
Virginia State Route 378
| Preceded by 377 |
Lists of highways 378 |
Succeeded by 379 |