William R. Burke (November, 1865 – March 17, 1939) was an American professional baseball pitcher and outfielder, who played in 1887 with the Detroit Wolverines, of the National League. He threw right-handed. Burke had a 0–1 record, with a 6.00 ERA, in two games, in his one-year career. He also had 2 hits in 8 at-bats.

• Career statistics from Baseball Reference, or Baseball Reference (Minors)
• Bill Burke Memorial at Find A Grave