Two Hearts or 2 Hearts may refer to:

• Two Hearts (Dave Mason album) or the title song, 1987
• Two Hearts (Jackie Evancho album), 2017
• Two Hearts (Men at Work album), 1985
• Two Hearts (Mary Hopkin album), 2023

• "Two Hearts" (The Charms song), or "Two Hearts, Two Kisses (Make One Love)", 1954
• "Two Hearts" (Cliff Richard song), 1988
• "Two Hearts" (John Parr song), 1986
• "Two Hearts" (Kish Mauve song), 2005; covered as "2 Hearts" by Kylie Minogue, 2007
• "Two Hearts" (Phil Collins song), 1988
• "Two Hearts" (Stephanie Mills song), 1981
• "Two Hearts" (Tohoshinki song), 2008
• "2 Hearts", by Digitalism from I Love You Dude, 2011
• "2 Hearts", by Sam Feldt and Sigma, 2020
• "2 Hearts", by Sugababes from Taller in More Ways, 2005
• "2 Hearts", by Toto from Kingdom of Desire, 1992
• "Two Hearts", by Anika Moa from Love in Motion, 2010
• "Two Hearts", by Bruce Springsteen from The River, 1980
• "Two Hearts", by Chris Isaak from San Francisco Days, 1993
• "Two Hearts", by Mango Groove from Mango Groove, 1989
• "Two Hearts," by Post Malone from F-1 Trillion, 2024
• "Two Hearts", by Ryan Adams from Easy Tiger, 2007

• Two Hearts (film), a 1943 Italian film directed by Carlo Borghesio
• 2 Hearts (film), a 2020 American film directed by Lance Hool
• Two Hearts (story), a 2005 novelette by Peter S. Beagle

• All pages with titles beginning with Two Hearts
• Two of Hearts (disambiguation)
• Time Lords, a fictional extraterrestrial race with two hearts in the TV series Doctor Who