Tome may refer to:

• Tome, Miyagi, city in Japan (formerly Tome District)
• Tome, New Mexico, an unincorporated community and census-designated place in New Mexico
  • Tome-Adelino, New Mexico, a former census-designated place in New Mexico

• Töme (born 1997), Canadian singer
• Gianfranco Labarthe Tome (born 1984), Peruvian footballer
• Jacob Tome (1810–1898), American philanthropist, founder of the Tome School
• Maria Tomé, São Toméan politician
• Norman Tome (born 1973), Australian football player
• Philippe Tome, pseudonym used by writer Philippe Vandevelde (1957-2019)
• Tome H. Walters Jr., American Air Force General
• Tomé (Angolan footballer) (born 1998)
• Tomé (Portuguese footballer) (born 1986)

• The Linux Game Tome, games website
• Makai Kingdom: Chronicles of the Sacred Tome, video game
• Tales of Maj'Eyal (ToME 4), a Roguelike computer game
• one of several rulebooks for Dungeons & Dragons:
  • Tome of Magic, handbook of rules and guidelines for Dungeons & Dragons
  • Tome of Battle: The Book of Nine Swords, rule supplement for Dungeons & Dragons
  • Tome and Blood, optional rulebook for Dungeons & Dragons

• Tome's spiny rat, Central-American spiny rat
• Tome School, prep school in North East, Maryland
• TV Tome, United States website for television information
• Tome Sculptures, album by band Agathodaimon
• Tome cheese, French cheese produced in the Alpine region
• TOME: Terrain of Magical Expertise, an animated web series by Chris Niosi

• Rotonda di San Tomè (Italian: Rotunda of St. Thomas), church in the comune of Almenno San Bartolomeo, in the province of Bergamo, Lombardy, Italy
• Tomos (Eastern Orthodox Church)
• Tomé (disambiguation)
• Tomb