Tirzah or Thyrza may refer to:

• Tirzah (name)
• To Tirzah, a poem by William Blake
• Tirzah (ancient city)
• Tirzah Stream
• Tirzah, South Carolina, a city of South Carolina
• the minor planet 267 Tirza
• the novel Thyrza by George Gissing
• Tirzah (musician), an English singer