Tarocin A and tarocin B are two structurally unrelated compounds that inhibit the TarO enzyme involved in teichoic acid biosynthesis in bacteria.[1]

Using either of them with β-lactam antibiotics seems to be effective in mice against some β-lactam-resistant bacteria.[1]

Because the tarocins lack activity when used alone it may simplify the clinical trials for approval for medical use.[1]

References

  1. ^ a b c Antibiotic Assistants; Scientists discover compounds that restore antibiotic efficacy against drug-resistant superbugs. March 2016

Further reading


Allikas: https://en.wikipedia.org/wiki/Tarocin
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