Ouse (/uːz/ ooz) may refer to:

• River Ouse, Yorkshire
• River Ouse, Sussex
• River Great Ouse, Northamptonshire and East Anglia
  • River Little Ouse, a tributary of the River Great Ouse

• Ouse, Tasmania, a town in Australia
• The Ouse, an estuary on Shapinsay, in the Orkney Islands, Scotland
• Grand River (Ontario), Canada, formerly known as the Ouse

• MV River Ouse, an Empire F type coaster in service with R H Hunt & Sons, Hull, 1947-52
• HMS Ouse (1905), a River-class destroyer of 1905

• Ouse Bridge (disambiguation)
• Oise a department in northern France
• Oise (river), a river in Belgium and northern France
• Ouseburn, a river in Tyne and Wear, England
• All articles with titles beginning with "Ouse"
• All articles with titles containing "Ouse"
• List of rivers of the United Kingdom