Pawlikowski (feminine Pawlikowska) is a Polish surname. Notable people with this surname include:

• Adam Pawlikowski (1925–1976), Polish film actor
• Aniela Pawlikowska, Polish artist
• Ellen M. Pawlikowski (born 1956), commander of the Space and Missile Systems Center of the United States' Air Force Space Command
• John T. Pawlikowski (born 1940), Servite priest and Professor of Social Ethics at the Catholic Theological Union
• Józef Pawlikowski (1767–1828), Polish noble
• Łukasz Pawlikowski (born 1997), Polish cellist
• Maciej Pawlikowski (born 1953), Polish mountaineer
• Maria Pawlikowska-Jasnorzewska, Polish poet
• Paweł Pawlikowski (born 1957), Polish BAFTA Award-winning filmmaker
• Zoogz Rift (born Robert Pawlikowski; 1953–2011), musician, painter and professional wrestling personality