Nojirimycin is the parent compound of a class of antibiotics and glycosidase inhibitors. Nojirimycin and its derivatives are mainly obtained from a class of Streptomyces species.[1] Chemically, it is an iminosugar.
Derivatives
- 1-deoxynojirimycin or duvoglustat
- 1-deoxygalactonojirimycin or migalastat, a drug for the treatment of Fabry disease
References
- ^ Inouye, S.; Tsuruoka, T.; Ito, T.; Niida, T. (1968). "Structure and synthesis of nojirimycin". Tetrahedron. 24 (5): 2125–44. doi:10.1016/0040-4020(68)88115-3. PMID 5636917.
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