Nifenazone is a drug that has been used as an analgesic for a number of rheumatic conditions.[1]

Synthesis

Nifenazone is the amide formed when ampyrone and the acid chloride of nicotinic acid are combined in a Schotten–Baumann reaction.[2][3]

See also

References

  1. ^ Hart FD, Boardman PL (June 1964). "Trial of Nifenazone ("Thylin")". British Medical Journal. 1 (5397): 1553–4. doi:10.1136/bmj.1.5397.1553. PMC 1814611. PMID 14133613.
  2. ^ Pongratz A, Zirm L (1957). "Über neue pharmakologisch wirksame Amide und Ester der Nicotinsäure". Monatshefte für Chemie. 88 (3): 330–335. doi:10.1007/BF00901766.
  3. ^ "Nifenazone". Pharmaceutical Substances. Georg Thieme Verlag KG. Retrieved 2024-07-16.
Allikas: https://en.wikipedia.org/wiki/Nifenazone
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