Murfreesboro is a city and the county seat of Rutherford County in the U.S. state of Tennessee.

Murfreesboro may also refer to:

• Murfreesboro, Arkansas, city in Pike County, Arkansas
• Murfreesboro, North Carolina, city in Hertford County, North Carolina

• One of three battles in the American Civil War
  • First Battle of Murfreesboro (July 13, 1862)
  • The Second Battle of Murfreesboro or the Battle of Stones River (December 31, 1862, to January 2, 1863)
  • Third Battle of Murfreesboro (December 5–7, 1864)