Masatomo (written: 政友, 政朋, 正朋 or 匡智) is a masculine Japanese given name. Notable people with the name include:
- Masatomo Kuba (久場 政朋, born 1984), Japanese footballer
- Masatomo Nakazawa (中澤 匡智, born 1983), Japanese actor, voice actor and singer
- Sumitomo Masatomo (住友 政友, 1585–1652), Japanese businessman
- Masatomo Taniguchi (谷口 正朋, born 1946), Japanese basketball player
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