Jack Ryan may refer to:

• Jack Ryan (footballer, born 1873) (1873–1931), Australian rules footballer for St Kilda
• Jack Ryan (footballer, born 1907) (1907–1959), Australian rules footballer for Hawthorn
• Jack Ryan (footballer, born 1914) (1914–1976), Australian rules footballer for Footscray and North Melbourne

• Jack Ryan (catcher) (1868–1952), MLB catcher and University of Virginia baseball coach
• Jack Ryan (outfielder) (1905–1967), MLB outfielder
• Jack Ryan (pitcher) (1884–1949), Major League Baseball pitcher

• Jack Ryan (English footballer) (born 1996), English footballer
• Jack Ryan (streetball player), American streetball player
• Jack Ryan (Moneygall hurler) (born 1946), Irish hurler and Gaelic footballer for Tipperary
• Jack Ryan (Roscrea hurler) (born 1927), Irish hurler for Tipperary
• Jack Ryan (runner), Australian masters long-distance runner

• Jack Ryan (designer) (1926–1991), designer and Zsa Zsa Gabor's sixth husband
• Jack Ryan (FBI agent) (born 1938), former FBI agent
• Jack Ryan (politician) (born 1959), former candidate for United States senator from Illinois and ex-husband of actress Jeri Ryan
• John M. Ryan (born 1949), American attorney

• Jack Ryan (character), a character in a series of novels by Tom Clancy
  • Jack Ryan (film series), based on Tom Clancy's character
  • Jack Ryan (TV series), an Amazon Video television series based on Tom Clancy's character
  • Jack Ryan: Shadow Recruit, a 2014 film based on Tom Clancy's character
• Jack Ryan, a character in the Bioshock video game series
• Jack Ryan, the titular character in a series of novels by Elmore Leonard; see Unknown Man No. 89
• Jack Ryan, a renegade DEA officer in a series of direct to video movies; see Cyborg Cop

• John Ryan (disambiguation)