Hirson is a surname. Notable people with the surname include:
- Alice Hirson (1929–2025), American actress
- Baruch Hirson (1921–1999), South African activist and historian
- David Hirson (born 1958), American dramatist
- Roger O. Hirson (1926–2019), American dramatist and screenwriter
See also
- Saša Hiršzon (born 1972), Yugoslavian/Croatian tennis player
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