Headspace may refer to:

• Headspace or ullage, the unfilled space in a container
• Headspace technology, the gaseous constituents of a closed space above liquids or solid emitting and vapors measured using headspace gas chromatography
• Headspace (firearms), a chamber measurement
• Headroom (photographic framing), a concept of aesthetic composition in imaging

• Headspace (company), an online healthcare company specializing in meditation
• Headspace (organisation), an Australian non-profit organization for youth mental health

• Headspace (slang), a term for mental world shared between multiple identities within the multiplicity (also called plurality) subculture

• Headspace (band), a British progressive metal band formed in 2006
• Headspace (Ashton Nyte album), 2005
• Headspace (Issues album), 2016
• Headspace (Pulse Ultra album), 2002
• "Headspace", a song by Lewis Capaldi from Divinely Uninspired to a Hellish Extent, 2019
• "Headspace", a song by Sharon Van Etten from We've Been Going About This All Wrong, 2022
• "Headspace", a song by Velvet Revolver from Contraband, 2004

• Headspace (film), a 2005 horror film
• "Headspace" (Ted Lasso), a 2021 TV episode
• Head-Space, a 2016 graphic novel