Grand Opera House may refer to:

• Grand Opera House, Sydney

• Grand Opera House (Toronto)

• Palais Garnier in Paris, often called the "Grand Opera House"

• Manila Grand Opera House

• Grand Opera House, Belfast, Northern Ireland
• Grand Opera House, York, England

Alphabetical by state, then city

• Grand Opera House (Los Angeles), California
• Grand Opera House (San Francisco), California
• Grand Opera House (Pueblo, Colorado), designed by Adler & Sullivan
• Grand Opera House (Wilmington, Delaware), NRHP-listed
• Degive's Grand Opera House, Atlanta, Georgia, NRHP-listed
• Grand Opera House (Macon, Georgia), NRHP-listed
• Beardstown Grand Opera House, Beardstown, Illinois, NRHP-listed
• Grand Opera House (Chicago), Illinois
• Grand Opera House (Dubuque, Iowa), NRHP-listed
• Ford's Grand Opera House, Baltimore, Maryland
• Grand Opera House (Boston), Massachusetts
• Grand Opera House (St. James, Minnesota), NRHP-listed
• Grand Opera House (Meridian, Mississippi), NRHP-listed
• Grand Opera House (St. Louis), Missouri
• Grand Opera House (Brooklyn), New York
• Grand Opera House (Manhattan), New York City
• Vale Hotel and Grand Opera House, Vale, Oregon, NRHP-listed
• Grand 1894 Opera House (Galveston, Texas), NRHP-listed
• Grand Opera House (Uvalde, Texas), NRHP-listed
• Grand Opera House (Seattle), Washington
• Grand Opera House (Ashland, Wisconsin)
• Oshkosh Grand Opera House, Wisconsin, NRHP-listed