George Walker may refer to:

• George Walker (chess player) (1803–1879), English chess player and writer
• George Walker (composer) (1922–2018), American composer
• George Walker (illustrator) (1781–1856), author of The Costume of Yorkshire
• George Walker (novelist) (1772–1847), English gothic novelist
• George Walker (printmaker) (born 1960), Canadian writer, artist and printmaker
• George Walker (privateer) (died 1777), British privateer
• George Walker (Puritan) (1581–1651), English clergyman
• George Walker (vaudeville) (1873–1911), American vaudeville singer, partner of Bert Williams
• Benjamin Walker (author) (George Benjamin Walker, 1913–2013), author on religion and philosophy, and authority on esoterica
• George F. Walker (born 1947), Canadian playwright and screenwriter
• George P. L. Walker (1926–2005), volcanologist
• George T. Walker (1913–2011), president of the University of Louisiana at Monroe, 1958–1976

• George Alfred Walker (1929–2011), British businessman, founder of Brent Walker
• George Herbert Walker (1875–1953), American businessman, grandfather of George Herbert Walker Bush
• George Herbert Walker Jr. (1905–1977), co-founder of the New York Mets baseball team
• George Herbert Walker IV (born 1969), chairman and chief executive officer, Neuberger Berman
• George Paterson Walker (1864–1926), oldest son of whisky maker Alexander Walker
• George Walker (CPR president), president of the Canadian Pacific Railway

• Sir George Walker, 1st Baronet (1764–1842), British general, of the Forestier-Walker baronets
• George Walker (attorney) (1824–1888), Massachusetts state congressman, banker, corporate executive, political adviser, advocate for bimetallism and U.S. Consul-General in Paris
• George Walker (Kentucky politician) (1763–1819), U.S. senator from Kentucky
• George Walker (soldier) (c. 1645–1690), clergyman and English colonel in Ireland
• George Gustavus Walker (1831–1897), British Conservative Member of Parliament
• George Walker (MP for Rossendale) (1874–1954), British Member of Parliament for Rossendale, 1945–1950
• George Herbert Walker III (1931–2020), American businessman, US ambassador to Hungary
• George J. Walker (1934–2005), U.S. general, military intelligence

• George Walker (Australian footballer) (1894–1973), Australian rules footballer
• George Walker (1880s pitcher) (1856–1908), Canadian Major League Baseball player
• George Walker (cricketer, born 1919) (1919–1995), English cricketer
• George Walker (cricketer, born 1984), English cricketer
• George Walker (footballer, born 1877) (1877–1930), English football full-back with Crystal Palace
• George Walker (footballer, born 1909) (1909–?), Scottish international footballer
• George Walker (footballer, born 1934) (1934–2012), English football inside forward with Bristol City and Carlisle United
• George Walker (1930s pitcher) (1915–1967), American Negro leagues baseball player
• George Walker (wrestler), Canadian wrestler
• George Glossop Walker (1860–1908), English cricketer
• George R. Walker, American football and basketball coach, and former hurdler
• George Croxton Walker, British military officer

• George Walker (mathematician) (c. 1730–1807), English Dissenter and mathematician
• George H. Walker (1811–1866), helped found Milwaukee, Wisconsin
• George W. Walker (1896–1993), automotive industrial designer
• George Washington Walker (1800–1859), missionary for the church called Religious Society of Friends, or Quakers
• Sir George Casson Walker, British administrator in the Indian Civil Service
• George Walker (South Africa), one of the alleged discoverers of the main gold reef on the Witwatersrand
• George Walker, member of Ken Kesey's Merry Pranksters and first husband of Carolyn Garcia