Francis or Frank Barrett may refer to:

• Francis Barrett (occultist) (c. 1780–after 1802), English occult writer
• Francis Thornton Barrett (1838–1919), British librarian
• Frank Barrett (footballer) (1872–1907), Scottish football goalkeeper
• Frank Barrett (Irish republican) (1892–1931), Irish officer during War of Independence and Irish Civil War
• Frank A. Barrett (1892–1962), American soldier, lawyer and politician
• Frank Barrett (baseball) (1913–1998), pitcher
• Frank Barrett (writer) (born 1953), British writer
• Francie Barrett (born 1977), Irish boxer