Emil "Tom" Frei III (February 21, 1924 – April 30, 2013) was an American physician and oncologist. He was the former director and former physician-in-chief of the Dana–Farber Cancer Institute in Boston, Massachusetts. He was also the Richard and Susan Smith Distinguished Professor of Medicine at Harvard Medical School.[1]

Early life and education

Frei was born in 1924 in St. Louis.[2] His mother nicknamed him Tom after Tom Sawyer.[3] His family owned the stained glass manufacturer Emil Frei & Associates.

He was inspired to study science after reading Hans Zinsser's book Rats, Lice and History.[3] Frei completed an accelerated pre-med Colgate University in 1944 after only 2 years of study[4] and his medical degree from Yale University in 1948.

Career

He interned at Firmin Desloge Hospital, now St. Louis University Hospital in St. Louis, Missouri and served as a physician in the Korean War. He worked at the National Cancer Institute from 1955 to 1965 and the M. D. Anderson Cancer Center from 1965 to 1972; while at M.D. Anderson he was the founding director of the Department of Development Therapeutics, which evolved into the Clinical Research Center. He served as physician-in-chief at the Dana-Farber Institute from 1972 to 1991. He is best known for his work on the treatment of lymphomas and childhood and adult leukemia.[5] His groundbreaking research into then-controversial combination chemotherapy, including the VAMP regimen, earned him many awards.[4][6]

He coauthored Holland–Frei Cancer Medicine with James F. Holland.[7]

Involvement in Cancer Cooperative Group Research

Frei was one of the founders of the Acute Leukemia Group B which later evolved into the Cancer and Leukemia Group B (CALGB). He served as the group chair for 16 years, from 1956 to 1963, and again from 1981 to 1990.[8]

Journal of Clinical Oncology

He coined the Journal of Clinical Oncology in 1981, journal published first issue in 1983 in association with American Society of Clinical Oncology.[9]

Recognition

Dr. Emil Frei with Edna Jones in 1972

In 1972 he received the Lasker-DeBakey Clinical Medical Research Award from the Lasker Foundation "for his outstanding contribution in application of the concept of combination chemotherapy for lymphoma and acute adult leukemia."[10] Other awards included the Jeffrey A. Gottlieb Memorial Award (1978); NIH Distinguished Alumni Award (1990); Fellow, American Academy of Arts and Sciences (1999); Pollin Prize for Pediatric Research (2003); and AARC Lifetime Achievement Award (2004).[11]

Death

Frei died of Parkinson's disease at his home in Oak Park, Illinois on April 30, 2013. He was 89.[2]

See also

References

  1. ^ "Official biography". Dana–Farber Cancer Institute. Archived from the original on 4 March 2016. Retrieved 13 March 2013.
  2. ^ a b Fox, Margalit (4 May 2013). "Emil Frei III, Who Put Cancer Cures in Reach, Dies at 89". The New York Times. Retrieved 5 May 2013.
  3. ^ a b Holland, James F.; Freireich, Emil J. (2013-10-20). "Emil Frei III, 1924-2013". Journal of Clinical Oncology. 31 (30): 3727–3730. doi:10.1200/JCO.2013.51.8126. ISSN 0732-183X.
  4. ^ a b "Emil Frei III, MD: In Memoriam (1924–2013) | Cancer Research".
  5. ^ "Emil Frei III". Animals in Research. National Institutes of Health. Archived from the original on 30 October 2011. Retrieved 13 March 2013.
  6. ^ Mukherjee, Siddhartha (2011). The Emperor of All Maladies. NY: Scribbler. pp. 139–142.
  7. ^ "James F. Holland, physician who helped show chemotherapy could treat cancer, dies at 92". The Washington Post.
  8. ^ "History of CALGB". Archived from the original on 2015-09-07. Retrieved 2013-05-01.
  9. ^ Bertino, Joseph R. (1983). "Editorial: A journal for Oncologists". Journal of Clinical Oncology. 1 (1): 1. doi:10.1200/JCO.1983.1.1.1.
  10. ^ "Lasker Award". National Institutes of Health. Retrieved 13 March 2013.
  11. ^ "Biographical note: Emil Frei, III". Making Cancer History Voices Collection. University of Texas Archival Resources Online. Retrieved 13 March 2013.
  12. ^ "Golden Plate Awardees of the American Academy of Achievement". www.achievement.org. American Academy of Achievement.
Allikas: https://en.wikipedia.org/wiki/Emil_Frei_III
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